TRUQAP in combination with abiraterone + prednisone

Potential side effects

Potential side effects with   TRUQAP  

TRUQAP may cause side effects, which may sometimes be severe, including:

High Blood Sugar Levels Icon High Blood Sugar Levels Icon

High blood sugar levels

  • High blood sugar levels, known as hyperglycemia, are common with TRUQAP and can be severe
  • Hyperglycemia has happened in people with and without a history of diabetes
  • Untreated severe hyperglycemia can lead to a condition called diabetic ketoacidosis, which is a serious condition that requires treatment in a hospital and can lead to death. It is possible to develop diabetic ketoacidosis while taking TRUQAP
  • Your doctor will monitor your blood sugar levels before you start and during treatment with TRUQAP
  • It is not known if TRUQAP is safe in people with type 1 diabetes or people who use insulin to treat their diabetes
  • If you have a history of diabetes, your doctor will monitor your blood sugar levels more often
  • If you have a fever, chills, infection, serious injury, or new illness, tell your healthcare provider before taking your next dose
  • Tell your doctor right away if you develop symptoms of high blood sugar, including:
    • excessive thirst
    • dry mouth
    • more frequent urination than usual or a bigger amount of urine than normal
    • blurred vision
    • increased appetite with weight loss
    • stomach area (abdominal) pain
    • unusual tiredness
    • confusion
    • nausea
    • vomiting
    • fruity odor on breath
    • dry or flushed skin
    • difficulty breathing
    • sleepiness
  • Tell your doctor right away if you develop symptoms of high blood sugar, including:
    • excessive thirst
    • dry mouth
    • more frequent urination
      than usual or a bigger
      amount of urine than normal
    • blurred vision
    • increased appetite with weight loss
    • stomach area (abdominal) pain
    • unusual tiredness
    • confusion
    • nausea
    • vomiting
    • fruity odor on breath
    • dry or flushed skin
    • difficulty breathing
    • sleepiness
Diarrhea IconDiarrhea Icon

Diarrhea

  • Diarrhea is common during treatment and can be severe
  • Talk to your doctor if you develop any signs of diarrhea, including loose or watery stool
  • Your doctor will tell you to drink more fluids and may prescribe medication to treat diarrhea
Skin Reactions IconSkin Reactions Icon

Skin reactions

  • Skin reactions are common with TRUQAP and can be severe
  • Tell your doctor or get medical help right away if you experience a new or worsening rash; reddening of the skin; a fever; blistering of the lips, eyes, or mouth; blisters on the skin; skin peeling; or dry skin

Among patients who experienced rash and diarrhea, these symptoms usually appeared within the first 2 weeks of treatment.

Explore tips for managing side effects

Most common side effects:

  • Skin reactions
  • Diarrhea
  • Tiredness
  • Changes in certain blood tests

Be sure to tell your doctor if you experience any side effects, even if they appear minor. It’s important to address them before they get worse.

These are not all the possible side effects of TRUQAP. For more information, ask your doctor, nurse, or pharmacist.

Please see full Important Safety Information below.

You may report side effects
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Side effect management

Your healthcare team can   help  

Your healthcare team can help

You may experience side effects at any time while taking TRUQAP + abiraterone + prednisone. Before treatment even starts, it's important to talk with your doctor about common side effects as they may have tips for making yourself more comfortable.

Tell your doctor about any side effects you may experience.

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Your doctor may adjust your treatment plan if you get certain serious side effects.

What you can do to help

Below are some common side effects you may experience while taking TRUQAP + abiraterone + prednisone and some suggestions that may help you manage them.

Diarrhea IconDiarrhea Icon

Tips to help manage diarrhea

Ask your doctor about over-the-counter treatments that you could have on hand that may help if you have diarrhea. Once you begin treatment, try to stay hydrated and limit foods that could be irritating to your digestive tract. Tell your doctor if you develop any signs of diarrhea (loose or watery stool).

  • Call your doctor at the first sign of diarrhea
  • Increase fluid intake
  • Eat less dairy
  • Avoid spicy foods
  • Limit caffeine intake
  • Taking TRUQAP with food may help
    reduce the risk of getting diarrhea*
Skin Reactions IconSkin Reactions Icon

Tips to help manage rashes and skin reactions

At the first sign of skin irritation, call your doctor. Your doctor may recommend over-the-counter creams or prescriptions.

  • Avoid body washes and lotions with dyes and perfumes
  • Switch to dye- and fragrance-free detergent
  • Wear cotton or linen fabrics
Nausea IconNausea Icon

Tips to help manage nausea

If you’re experiencing nausea while taking TRUQAP in combination,† try to avoid foods and drinks that can make you feel worse.

  • Eat small meals more often
  • Avoid strong smells
  • Drink clear, cold beverages
Tiredness IconTiredness Icon

Tips to help manage tiredness

Managing tiredness means rest and delegation—save your energy as much as you can for the things that matter! Here are a few tips to help:

  • Delegate chores
  • Schedule time to relax
  • Exercise

Ask your doctor before starting any new physical activity or exercise regimen.

*Based on an early study in healthy participants.

†Combination therapy: TRUQAP + abiraterone + prednisone.

Keep track of side effects and treatment-related notes with the TRUQAP Side
Effect Tracker

TRUQAP Side Effect Tracker download icon
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If you experience any symptoms, talk to your doctor right away.

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